BREAST
LUNG
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STOMACH
OVARIAN
HEAD & NECK
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New Cases Per Year

Early Detection Survival Rate

Development chance

The overall 5-year survival rate for breast cancer is now 89%—a dramatic improvement over the early 1960s when the rate was 63%. When considered by stage, the 5-year survival rates are 99% for localized disease and 85% for regionally advanced disease.

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Breast cancer is the most commonly diagnosed cancer among women worldwide. Each year, breast cancer accounts for 12 percent of all cancers diagnosed globally, and it is the second leading cause of cancer-related death among women.

Different tests can be used to look for and diagnose breast cancer. If your doctor finds an area of concern on a screening test (a mammogram), or if you have symptoms that could mean breast cancer, you will need more tests to know for sure if it’s cancer.

The most common symptom of breast cancer is a new lump or mass. A painless, hard mass that has irregular edges is more likely to be cancer, but breast cancers can be tender, soft, or rounded. They can even be painful. For this reason, it is important to have any new breast mass, lump, or breast change checked by a health care professional experienced in diagnosing breast diseases.

For both DCIS and early-stage invasive breast cancer, doctors generally recommend surgery to remove the tumor. To make sure that the entire tumor is removed, the surgeon will also remove a small area of healthy tissue around the tumor.

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New cases each year

Caused by smoking

of all cancers

Lung cancer is the most common cause of cancer mortality globally, responsible for nearly 1 in 5 cancer-related deaths, or an estimated 1.6 million people. Lung cancer is by far the leading cause of cancer-related death among both men and women; more deaths are caused by lung cancer every year than by breast, prostate, and colon cancer combined.

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Cancer of the lung, like all cancers, results from an abnormality in the body's basic unit of life, the cell. Disruption of this system of checks and balances on cell growth results in an uncontrolled division and proliferation of cells that eventually forms a mass known as a tumor.

Diagnosis is the process of finding out the cause of a health problem. Diagnosing lung cancer usually begins with a visit to your family doctor. Your doctor will ask you about any symptoms you have and may do a physical exam. Based on this information, your doctor may refer you to a specialist or order tests to check for lung cancer or other health problems.

Most lung cancers do not cause any symptoms until they have spread, but some people with early lung cancer do have symptoms. If you go to your doctor when you first notice symptoms, your cancer might be diagnosed at an earlier stage, when treatment is more likely to be effective.

People with an increased risk of lung cancer may consider annual lung cancer screening using low-dose CT scans. Lung cancer screening is generally offered to people 55 and older who smoked heavily for many years and are otherwise healthy. Discuss your lung cancer risk with your doctor. Together you can decide whether lung cancer screening is right for you.

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New cases each year

Early survival chance

chance of developing

Colorectal cancer is one of the major cancer types for which new immune-based cancer treatments are currently in development. Colorectal cancer is the third most common type of cancer among both men and women.

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Colorectal cancer begins in the lining of the colon or rectum. It can spread deeper into the colon or rectum wall or, in the case of advanced cancer, into other organs and lymph nodes. Over 95% of colorectal cancers are adenocarcinomas, a type of tumor that originates in the mucus-producing glands of the colon or rectum.

Doctors use many tests to find, or diagnose, cancer. They also do tests to learn if cancer has spread to another part of the body from where it started. If this happens, it is called metastasis. For example, imaging tests can show if the cancer has spread. Imaging tests show pictures of the inside of the body. Doctors may also do tests to learn which treatments could work best.

A change in your bowel habits, including diarrhoea or constipation or a change in the consistency of your stool, that lasts longer than four weeks, rectal bleeding or blood in your stool, persistent abdominal discomfort, such as cramps, gas or pain, a feeling that your bowel doesn't empty completely. Many people with colon cancer experience no symptoms in the early stages of the disease. When symptoms appear, they'll likely vary, depending on the cancer's size and location in your large intestine.

Treatment for colon cancer is based largely on the stage (extent) of the cancer, but other factors can also be important. People with colon cancers that have not spread to distant sites usually have surgery as the main or first treatment. Chemotherapy may also be used after surgery (called adjuvant treatment). Most adjuvant treatment is given for about 6 months.

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New cases each year

Early survival chance

Most common cancer

Stomach cancer begins when cancer cells form in the inner lining of your stomach. These cells can grow into a tumour. Also called gastric cancer, the disease usually grows slowly over many years. If you know the symptoms it causes, you and your doctor may be able to spot it early, when it’s easiest to treat.

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Scientists don’t know exactly what makes cancer cells start growing in the stomach. But they do know a few things that can raise your risk for the disease. One of them is infection with a common bacteria, H. pylori, which causes ulcers. Inflammation in your gut called gastritis, a certain type of long-lasting anemia called pernicious anemia, and growths in your stomach called polyps also can make you more likely to get cancer.

Doctors typically don't do routine screening for stomach cancer. That's mainly because it's not that common, so getting extra tests often isn't helpful. If you're at higher risk for it though, talk to your doctor to see how to keep an eye out for it. You may get some of the same tests that you would get if you had symptoms and were looking for a diagnosis.

Just having indigestion or heartburn after a meal doesn’t mean you have cancer. But if you feel these symptoms a lot, talk to your doctor. He can see if you have other risk factors and test you to look for any problems. As stomach tumors grow, you may have more serious symptoms, such as: Stomach pain, blood in your stool, weight loss for no reason, trouble swallowing, yellowish eyes or skin, swelling in your stomach, constipation or diarrhoea, weakness or feeling tired or heartburn.

Many treatments can fight stomach cancer. The one you and your doctor choose will depend on how long you've had the disease or how much it has spread in your body, called the stage of your cancer.

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Ovarian cancers are epithelial cancers

Of ovarian cancer patients will see recurrence of disease

Types of immunotherapy clinical trials

Ovarian cancer is the leading cause of death from gynaecological cancer. Ovarian cancer is sometimes called “the cancer that whispers,” because the disease often progresses before symptoms arise. Nine out of 10 ovarian cancers are epithelial ovarian cancers.

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Despite advances in surgery and chemotherapy over the past 20 years, only modest progress has been made in improving overall survival in patients with ovarian cancer. Although the majority of women with advanced ovarian cancer respond to first-line chemotherapy, most responses are not durable. More than 80% of patients will have a recurrence of their disease after first-line treatment.

Blood tests might include organ function tests that can help determine your overall health.Your doctor might also test your blood for tumor markers that indicate ovarian cancer. For example, a cancer antigen (CA) 125 test can detect a protein that's often found on the surface of ovarian cancer cells. These tests can't tell your doctor whether you have cancer, but may give clues about your diagnosis and prognosis.

Symptoms of ovarian cancer may be confused with less serious, noncancerous conditions. Symptoms may include Abdominal bloating, indigestion or nausea. Changes in appetite, such as a loss of appetite or feeling full sooner. Pressure in the pelvis or lower back, a more frequent or urgent need to urinate and/or constipation, changes in bowel movements.

For some women with very early stage ovarian cancer, surgery is the only treatment you need. Most women with ovarian cancer are diagnosed with advanced disease and have a combination of surgery and chemotherapy. You may have chemotherapy after surgery, or both before and after surgery.

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New cases each year

Early survival chance

Most common cancer

Head and neck cancer is highly curable—often with single-modality therapy (surgery or radiation)—if detected early. More advanced head and neck cancers are generally treated with multi-modality surgery, including various combinations of surgery, radiation, and chemotherapy.

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Head and neck cancer is a group of cancers that starts in or near your throat, voice box, nose, sinuses, or mouth. Usually, it begins in the cells that line the surfaces of these body parts. Doctors call these squamous cells. There are five main types of head and neck cancer. They’re named for the specific part of your head or neck they affect.

Doctors use many tests to find, or diagnose, cancer. They also do tests to learn if cancer has spread to another part of the body from where it started. Doctors may also do tests to learn which treatments could work best.For most types of cancer, a biopsy is the only sure way for the doctor to know whether an area of the body has cancer.

Swelling or a sore that does not heal, red or white patch in the mouth, lump, bump, or mass in the head or neck area, with or without pain, persistent sore throat, foul mouth odor, hoarseness or change in voice, nasal obstruction or persistent nasal congestion, frequent nose bleeds and/or unusual nasal discharge, difficulty breathing, double vision, Numbness or weakness of a body part in the head and neck region, pain or difficulty chewing, swallowing, or moving the jaw or tongue.

Many cancers of the head and neck can be cured, especially if they are found early. Although eliminating the cancer is the primary goal of treatment, preserving the function of the nearby nerves, organs, and tissues is also very important. When planning treatment, doctors consider how treatment might affect a person’s quality of life, such as how a person feels, looks, talks, eats, and breathes.

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New cases each year

Early survival chance

chance of developing

It is more common for cancer that started in another part of the body to spread to the liver. This is not liver cancer, but rather “metastatic cancer” of another organ. For instance, pancreatic, colon, stomach, breast, lung, or other cancer that has spread to the liver is still named according to the organ in which it started.

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Cirrhosis develops when liver cells are damaged and replaced by scar tissue. Most cirrhosis in the United States is caused by alcohol abuse. Other causes are NAFLD, viral hepatitis (types B and C, as described below), too much iron in the liver from a disease called hemochromatosis, and some other rare types of chronic liver disease. Combined alcohol abuse and hepatitis virus infection puts people at high risk of cirrhosis and HCC.

People with HCC may experience no symptoms, particularly when the tumor is detected early as part of a screening program. When symptoms or signs do occur, they include: Pain, especially at the top right of the abdominal area, near the right shoulder blade, or in the back, Unexplained weight loss, A hard lump under the ribs on the right side of the body, which could be the tumor or a sign that the liver has gotten bigger, Weakness or fatigue.

When a tumor is found at an early stage and the patient’s liver is working well, treatment is aimed at trying to eliminate the cancer. The care plan may also include treatment for symptoms and side effects, an important part of cancer care. When liver cancer is found at a later stage, or the patient’s liver is not working well, the patient and doctor should talk about the goals of each treatment recommendation.

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New cases each year

Early survival chance

Most common cancer

In its early stages, kidney cancer typically has no symptoms. As a tumor grows, symptoms may include blood in the urine, pain or a lump in the lower back or abdomen, fatigue, weight loss, and swelling in the ankles or legs. If kidney cancer is diagnosed while the cancer is still local, the 5-year survival rate is 92%.

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Tumor that causes Kidney Cancer, can be malignant, indolent, or benign. A malignant tumor is cancerous, meaning it can grow and spread to other parts of the body. An indolent tumor is also cancerous, but this type of tumor rarely spreads to other parts of the body. A benign tumor means the tumor can grow but will not spread.

Doctors do tests to learn about the cancer and also to know if cancer has spread to another part of the body from where it started. Doctors may also do tests to learn which treatments could work best. For most types of cancer, a biopsy is the only sure way for the doctor to know whether an area of the body has cancer.

Blood in the urine, Pain or pressure in the side or back, A mass or lump in the side or back, Swelling of the ankles and legs, High blood pressure, Anemia, which is a low red blood cell count, Fatigue, Loss of appetite, Unexplained weight loss, Fever that keeps coming back and is not from a cold, flu, or other infection.

Kidney cancer is most often treated with surgery, targeted therapy, immunotherapy, or a combination of these treatments. Radiation therapy and chemotherapy are occasionally used. People with kidney cancer that has spread, often receive multiple lines of therapy. This means treatments are given one after another.

New cases each year

Early survival chance

chance of developing

Glioblastoma (GBM) is the most dangerous and aggressive form of brain cancer. For newly diagnosed GBM patients treated with current standard of care, median progression free survival is just 6.9 months, and median overall survival is 14.6 months. Fewer than 10% of patients survive more than 5 years.

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As a group, gliomas are one of the most common types of brain tumors. A glioma is a tumor that grows from a glial cell. A glial cell is a type of supportive cell in the brain. The main types of supportive cells in the brain include astrocytes, oligodendrocytes, and ependymal cells. Gliomas may be considered astrocytomas, oligodendrogliomas, or ependymomas.

Often a brain tumor is initially diagnosed by an internist or a neurologist. In addition to asking the patient for a detailed medical history and doing a physical examination, the doctor may recommend the tests. These tests are to help find out the presence, and perhaps the type or grade, of a brain tumor.

A general symptom of a brain is caused by the pressure of the tumor on the brain or spinal cord. Specific symptoms are caused when a specific part of the brain is not working well because of the tumor. For many people with a brain tumor, they were diagnosed when they went to the doctor after experiencing a problem, such as a headache or other changes.

For a low-grade brain tumor, surgery may be the only treatment needed especially if all of the tumor can be removed. If there is visible tumor remaining after surgery, radiation therapy and chemotherapy may be used. For higher-grade tumors, treatment usually begins with surgery, followed by radiation therapy and chemotherapy.

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New cases each year

Early survival chance

Most common cancer

Cervical cancer is the fourth most frequently diagnosed cancer among women worldwide. Globally, there are approximately 530,000 cases of cervical cancer per year, and 265,000 deaths. If cervical cancer is caught while it is still localized, the 5-year survival rate is 91%.

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Cervical cancer begins when healthy cells on the surface of the cervix change and grow out of control, forming a mass called a tumor. In some cases, a hysterectomy is needed to prevent cervical cancer. A hysterectomy is the removal of the uterus and cervix.

The doctor may do a colposcopy to check the cervix for abnormal areas. Colposcopy can also be used to help guide a biopsy of the cervix. A special instrument called a colposcope is used. Other tests can suggest that cancer is present, but only a biopsy can make a definite diagnosis. A pathologist then analyzes the sample(s).

Most women do not have any signs or symptoms of a precancer. In many women with early-stage cervical cancer, symptoms are typically seen. In women with advanced and metastatic cancers, the symptoms may be more severe depending on the tissues and organs to which the disease has spread.

Surgery is the removal of the tumor and some surrounding healthy tissue during an operation. Radiation therapy may be given alone, before surgery, or instead of surgery to shrink the tumor.

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